Rice based ORS versus glucose-ORS in non-cholera diarrhea in children

Rice vs. Glucose ORS in Pediatric Diarrhea

Abstract

Abstract

Objective: To compare the mean reduction in frequency of stool with use of rice-based ORS versus glucose-ORS in children with non-cholera acute watery diarrhea.

Material and Methods: This randomized clinical trial was conducted in department of Pediatrics, King Edward Medical University/ Mayo Hospital Lahore from January to July 2020. Total of 80 patients (40 in each group) were enrolled by simple random sampling and were randomized into group-A (Rice-based ORS) and group-B (Glucose-ORS). Age and change in number of stools were compared using Mann-Whitney U test in both groups (Glucose ORS and Rice based ORS) as data was not normal (Shapiro-Wilk test was used). Chi-square test was applied to compare gender and duration of diarrhea in both the groups. P-value ≤ 0.05 was taken as significant.

Results: The mean age of patients was 5.94 ± 3.80 years and 4.66 ± 3.11 years in rice-based ORS group and glucose-based ORS respectively. Mean change in number of stool in group-A was 1.92 ±0.83 and in group-B it was 2.87 ± 0.82. The mean change in number of stool was statistically higher in group-B when compared to group-A (p-value < 0.001).

Conclusion: Glucose based ORS is better than rice-based ORS in reducing the number of stools in children with non-cholera acute watery diarrhea.

Key Words Oral rehydration salt, Rice based ORS, Glucose ORS, Non-cholera, Acute watery diarrhea.